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Technical Slide Library

PowerPoint Download

Subject

  • Fibrin sealants & components
  • Components of fibrin sealants
  • Thrombin
  • Aprotinin
  • Mechanism of action
  • Clinical safety of Beriplast® P Combi-Set
  • Beriplast® P Combi-Set: integrated safety system
  • Beriplast® P Combi-Set ISS: controls
  • Beriplast® P Combi-Set: NAT/PCR used to test plasma donations
  • Beriplast® P Combi-Set ISS: virus inactivation and elimination
  • Validation of virus Inactivation/elimination
  • Viral reduction in Beriplast® P Combi-Set production
  • Beriplast® P Combi-Set log10 viral reduction factors: human fibrinogen
  • Aprotinin and transmissible spongiform encephalopathy (TSE) risk
  • Beriplast® P Combi-Set: adverse reactions
  • Estimated risks of adverse events in clinical practice
  • Beriplast® P Combi-Set: conclusions
  • Experimental models
  • Fibrin sealants increase the tensile strength of ruptured membranes in vitro
  • Fibrin sealants strengthen colonic anastomoses
  • Fibrin sealants strengthen vascular anastomoses
  • Fibrin sealant reduces suture hole bleeding in a pig vascular graft model
  • Effective haemostasis with fibrin sealant in experimental liver injury
  • Comparison of two commercially available fibrin sealants
  • Less force needed to deliver low viscosity fibrin sealants through delivery devices
  • Strength of adhesion is inversely related to treatment viscosity
  • Delivery devices
  • Pantajet® dual syringe in open surgery
  • Application of fibrin sealant in minimal invasive surgery
  • Application of fibrin sealant through double-lumen probe in endoscopy
  • Double-lumen probe (no needle) for use in endoscopy
  • Flexible catheter for spray delivery
  • Fibrin sealants
  • Fibrinogen
  • Factor XIII
  • Calcium chloride
  • Beriplast® P Combi-Set safety & tolerability
  • Safety of Beriplast® P Combi-Set
  • Beriplast® P Combi-Set ISS: safety at the source
  • Beriplast® P Combi-Set: window period reduction by PCR
  • Beriplast® P Combi-Set: virus elimination and inactivation steps
  • Beriplast® P Combi-Set: viruses used in validation studies
  • Beriplast® P Combi-Set log10 viral reduction factors: human thrombin
  • Beriplast® P Combi-Set log10 viral reduction factors: human factor XIII
  • Beriplast® P Combi-Set ISS: final product testing
  • Beriplast® P Combi-Set: drug surveillance
  • Safety of Beriplast® P Combi-Set
  • Preclinical uses of fibrin sealant
  • Fibrin sealants enhance tensile strength of intraocular wounds
  • Human plasma derived fibrin sealants produce strong wound closure
  • Fibrin sealants strengthen watertight sutures
  • Effect of fibrin sealant in a femoral artery injury model
  • Effective haemostasis in experimental atrial rupture
  • Viscosity and delivery of fibrin sealants
  • Viscosity of fibrin sealants
  • Fibrin sealant reduces rate of adhesion formation in a rat model
  • Fibrin sealant inhibits pericardial adhesions after cardiac surgery in dogs
  • Fibrin sealants
  • Application of fibrin sealant through spray tip in open surgery
  • Application of fibrin sealant in minimal invasive surgery
  • Application of fibrin sealant through double-lumen probe in endoscopy
  • Application of fibrin sealant with double-lumen cannulae in microsurgery
  • Flexible catheter